Optimizing the relaxivity of GdIII complexes appended to InP/ZnS quantum dots by linker tuning.

نویسندگان

  • Graeme J Stasiuk
  • Sudarsan Tamang
  • Daniel Imbert
  • Christelle Gateau
  • Peter Reiss
  • Pascal Fries
  • Marinella Mazzanti
چکیده

Three bimodal MRI/optical nanosized contrast agents with high per-nanoparticle relaxivity (up to 2523 mM(-1) s(-1) at 35 MHz and 932 mM(-1) s(-1) at 200 MHz) have been prepared connecting up to 115 tris-aqua Gd(III) complexes to fluorescent non-toxic InP/ZnS quantum dots. The structure of the linker has an important effect on the relaxivity of the final multimeric contrast agent.

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عنوان ژورنال:
  • Dalton transactions

دوره 42 23  شماره 

صفحات  -

تاریخ انتشار 2013